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Antigenic Specificity | MARCH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC); Immunofluorescence (IF); Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of MARCH2 in human and rat. E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86; and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6. |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MARCH2 |
Other Names | [RNF172; E3 ubiquitin-protein ligase MARCH2; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; MARCH-II; RING finger protein 172], [MARCH2; MARCH2; RNF172; HSPC240; MARCH-II; RNF172; MARCH-II] |
Gene, Accession # | [MARCH2], Gene ID: 51257, NCBI: NP_001005415.1, UniProt: Q9P0N8 |
Catalog # | MBS846056 |
Price | $345 |
Order / More Info | MARCH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |