Mouse CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD40
Clone[FGK4.5/FGK45]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionCD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Immunogenn/a
Other Names[Mouse CD40; Tumor necrosis factor receptor superfamily member 5; Cd40; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; Tnfrsf5]
Gene, Accession #[CD40], Gene ID: 21939, NCBI: NP_035741.2, UniProt: P27512
Catalog #MBS2553793
Price$90, $110
Order / More InfoMouse CD40 Antibody from MYBIOSOURCE INC.
Product Specific References1. Hasbold J, Johnson-Leger C, Atkins CJ, Clark EA, Klaus GG. Eur J Immunol. 1994; 24(8):1835-1842. 2. Hasbold J, Klaus GG. Eur J Immunol. 1994; 24(1):152-157. 3. Klaus GG, Holman M, Hasbold J. Eur J Immunol. 1994; 24(11):2714-2719. 4. Noelle RJ, Ledbetter JA, Aruffo A. Immunol Today. 1992; 13(11):431-433. 5. Parry SL, Hasbold J, Holman M, Klaus GG. J Immunol. 1994; 152(6):2821-2829.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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