ATXN3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATXN3
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman, mouse, rat, bovine, dog, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
Isotypen/a
Formatunconjugated
Size0.6 mg, 1.5 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDetects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. Ataxin 3. Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
ImmunogenImmunogen: Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli. Antigen: Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Other Names[ATXN3; AT3; ATX3; ataxin-3; ataxin 3 variant h; autosomal dominant ataxin 3; ataxin 3 variant m; ataxin 3 variant ref; JOS; josephin; Machado-Joseph; Machado-Joseph disease protein 1; MJD; MJD1; SCA3; spinocerebellar ataxia 3; olivopontocerebellar ataxia 3; spinocerebellar ataxia type 3 protein], [ATXN3; ATXN3; AT3; JOS; MJD; ATX3; MJD1; SCA3; RP11-529H20.5; ATX3; MJD; MJD1; SCA3]
Gene, Accession #[ATXN3], Gene ID: 4287, NCBI: NP_001121169.2, UniProt: P54252
Catalog #MBS448047
Price$300, $415
Order / More InfoATXN3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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