Bcl-6 (Follicular Lymphoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBcl-6 (Follicular Lymphoma Marker)
Clone[rBCL6/1527]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin
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DescriptionThe specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19, 000, full-length human proteins. Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predo
ImmunogenImmunogen: Recombinant fragment of human bcl-6 protein (around aa 256-389) Cellular Localization: Nuclear
Other Names[B-cell lymphoma 5 protein; B-Cell Lymphoma 6 Protein; BCL5; BCL6; BCL6A; cys his2 zinc finger transcription factor; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S]
Gene, Accession #[Bcl-6], Gene ID: 604, NCBI: NP_001124317.1, UniProt: P41182
Catalog #MBS4380207
Price$190, $340, $340
Order / More InfoBcl-6 (Follicular Lymphoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRee, H.J., et al. 2003. Hum. Pathol. 34: 610-616. Garcia JF, et al.2006.J. Histochem Cytochem.54:31.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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