Lamin A/C Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLamin A/C
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
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DescriptionLamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A, B and C. The lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C. Lamin A/C mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy and Hutchinson-Gilford progeria syndrome. Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.
ImmunogenImmunogen: Lamin A/C antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human Lamin A/C, identical to the related rat and Rabbit sequences, as the immunogen
Other Names[Affinity Purified Rabbit Lamin A/C; Lamin A/C; Lamin A/C; Lamin C; Lamin A]
Gene, Accession #[LMN1]
Catalog #MBS5312587
Price$345
Order / More InfoLamin A/C Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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