SIRT6 - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SIRT6 - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Chromatin IP (ChIP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against SIRT6. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SIRT6 is a NAD-dependent protein deacetylase. SIRT6 has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. SIRT6 modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. SIRT6 may be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. SIRT6 is required for genomic stability |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIRT6 |
| Other Names | [NAD-dependent protein deacetylase sirtuin-6 isoform 1; NAD-dependent protein deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; sirtuin 6; Regulatory protein SIR2 homolog 6; SIR2-like protein 6] |
| Gene, Accession # | [SIRT6], Gene ID: 51548, NCBI: NP_057623, UniProt: Q8N6T7 |
| Catalog # | MBS3200921 |
| Price | $335 |
| Order / More Info | SIRT6 - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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