CD3/CD28 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD3/CD28
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
FormatFITC/PE conjugate, 2-color reagent
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionThe CD3 epitope is expressed on the epsilon chain of the CD3/T cell antigen receptor (TcR) complex. CD3 is expressed on 65-85% of thymocytes and has a mitogenic effect on peripheral blood T cells. Identification of human T cells expressing the 22-28,000 M. W. surface antigen. Antihuman CD28 binds the 44kDa MW cell surface protein on the surface of most T cells. CD28 acts as the ligand for the B7/BB-1 molecule on the surface of activated B cells. B7/BB-1 co-stimulates T cells through CD28, along with CD2 and CD3. CD28 antigen is a disulfide-linked homodimeric glycoprotein. The CD28 antigen is present on approximately 60%-80% 0flymphocytes (95% of CD4 and 50% of CD8 lymphocytes). CD28 regulates the expression of cytokines by T cells, not only
ImmunogenImmunogen: CD3=Derived from the hybridization of mouse NS-1 myeloma celss with spleen cells from BALB/c mice immunized with human thymocytes. CD28=Derived from the hybridization of mouse Sp2/O-Ag14 myeloma cells with spleen cells of BALB/c mice immunized with the HPB-ALL T-cell line.
Other Names[CD3 FITC - CD28 PE], [CD3E; CD3E; T3E; TCRE; T3E]
Gene, Accession #[CD3 - CD28], Gene ID: 916, NCBI: NP_000724.1, UniProt: P07766
Catalog #MBS396143
Price$385
Order / More InfoCD3/CD28 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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