MAFA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAFA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.4 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total MAFA protein. Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor.Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.
ImmunogenImmunogen: Synthetic peptide of human MAFA
Other Names[hMafA; RIPE3b1]
Gene, Accession #[MAFA], Gene ID: 389692, NCBI: NP_963883.2, UniProt: Q8NHW3
Catalog #MBS9416164
Price$255
Order / More InfoMAFA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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