Complement C2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityComplement C2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionComponent C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
ImmunogenImmunogen Type: Recombinant protein Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 612 of Human C2
Other Names[complement C2 isoform 1 preproprotein; Complement C2; complement C2; complement component 2; C3/C5 convertase]
Gene, Accession #Gene ID: 717, NCBI: NP_000054
Catalog #MBS9403665
Price$320
Order / More InfoComplement C2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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