STAT3 (S727) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTAT3 (S727)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatProtein A purified
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis STAT3(S727) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 710-740 amino acids from the human region of human STAT3(S727). Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicr
Immunogenn/a
Other Names[Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF]
Gene, Accession #[STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763
Catalog #MBS9231352
Price$165, $370
Order / More InfoSTAT3 (S727) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAkira S.,et al.Cell 77:63-71(1994). Della Pietra L.,et al.Gene 213:119-124(1998). Feinstein E.,et al.Patent number EP2440214, 18-APR-2012. Ota T.,et al.Nat. Genet. 36:40-45(2004). Zody M.C.,et al.Nature 440:1045-1049(2006).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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