FAIM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAIM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionFAIM Antibody: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite
ImmunogenImmunogen: FAIM antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human FAIM. Buffer: FAIM Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[FAIM; FAIM1; FAIM1; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule], [FAIM; FAIM; FAIM1; FAIM1]
Gene, Accession #[FAIM], Gene ID: 55179, NCBI: NP_060617, UniProt: Q9NVQ4
Catalog #MBS150757
Price$375
Order / More InfoFAIM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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