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Antigenic Specificity | GDNF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene m |
Immunogen | Immunogen: Recombinant protein of human GDNF (NP 000505.1). |
Other Names | [glial cell line-derived neurotrophic factor isoform 5; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; glial cell derived neurotrophic factor; Astrocyte-derived trophic factor] |
Gene, Accession # | [GDNF], Gene ID: 2668, NCBI: NP_001265027.1, UniProt: P39905 |
Catalog # | MBS8569332 |
Price | $280 |
Order / More Info | GDNF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |