Edit |   |
Antigenic Specificity | FGFR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FGFR4 antibody is generated from rabbits immunized with recombinant human FGFR4 protein. FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. |
Immunogen | n/a |
Other Names | [Fibroblast growth factor receptor 4; FGFR-4; CD334; FGFR4; JTK2; TKF] |
Gene, Accession # | [FGFR4], Gene ID: 2264, NCBI: NP_002002.3, UniProt: P22455 |
Catalog # | MBS9209689 |
Price | $165, $370 |
Order / More Info | FGFR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jezequel, P., et al., Br. J. Cancer 90(1):189-193 (2004). Qian, Z.R., et al., J. Clin. Endocrinol. Metab. 89(4):1904-1911 (2004). Yu, S., et al., J. Biol. Chem. 278(22):19597-19602 (2003). Becker, N., et al., Cancer Epidemiol. Biomarkers Prev. 12(6):582-583 (2003). Takenaka, H., et al., Arch. Dermatol. Res. 294(7):331-338 (2002). |