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Antigenic Specificity | GABA Receptor B 1b (GBR1b) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg, 0.1 mg |
Concentration | ~1mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB). Other applications have not been tested |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes rat GBR1b. Peptide sequence is 100% conserved in various alternatively spliced rat GBR1b (844aa), GBR1c (875aa) and GBR1d (812aa). No significant sequence homology is detected with GBR1a or GBR2 or other GABA receptors. GABA (g-amino butyric acid) is the most abundant neurotransmitter in mammalian brain. GABA exerts its effects through ionotropic ligand-gated GABAA, GABAC and GABAB receptors (GABABRs). Presynaptic GABABRs inhibit neurotransmitter release by down regulating high voltage activated Ca+2 channels, whereas postsynaptic GABABRs decrease neuronal excitability by activating a prominent inwardly rectifying K+ (Kir) conductance that underlies the late inhibitory postsynaptic potential. Two N-terminal splice variants GABABR |
Immunogen | Immunogen: Synthetic peptide corresponding to a 16aa sequence near the N-terminus of rat GBR1b (KLH). Species Sequence Homology: Mouse: 100%. Human: 94% |
Other Names | [-GABA Receptor B 1b (GBR1b)], [gabarapa; gabarap; mg:bb02b03] |
Gene, Accession # | Gene ID: 326974, NCBI: AAH56701.1 |
Catalog # | MBS611586 |
Price | $470, $745 |
Order / More Info | GABA Receptor B 1b (GBR1b) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |