ADIPOQ Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADIPOQ
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionAdiponectin, also termed AdipoQ, Acrp30, apM1 and GBP28, is an adipokine expressed exclusively in brown and white adipocytes (1). It is secreted into the blood and exists in three major forms: a low molecular weight trimer, a medium molecular weight hexamer and a high molecular weight multimer (1). Adiponectin levels are decreased in obese and insulinresistant mice and humans (2), suggesting that this adipokine is critical to maintain insulin sensitivity. Adiponectin stimulates the phosphorylation of AMPKalpha at Thr172 and activates AMPK in skeletal muscle (3). It also stimulates glucose uptake in myocytes (3). The block of AMPK activation by a dominantnegative AMPKalpha2 isoform inhibits the effect of adiponectin on glucose uptake, indica
ImmunogenImmunogen: A synthetic -peptide of human ADIPOQ
Other Names[ADIPOQ; Adiponectin; Adiponectin; ADIPOQ; ACDC; ACRP30; ADIPQTL1; ADPN; APM1; APM1; GBP28; Adiponectin;], [ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1]
Gene, Accession #Gene ID: 9370, NCBI: NP_001171271.1, UniProt: Q15848
Catalog #MBS125135
Price$275, $430, $655
Order / More InfoADIPOQ Antibody from MYBIOSOURCE INC.
Product Specific References1. Kadowaki, T. et al. (2006) J. Clin. Invest. 116, 1784-1792. 2. Hu, E. et al. (1996) J. Biol. Chem. 271, 10697-10703. 3. Yamauchi, T. et al. (2002) Nat. Med. 8, 1288-1295. 4. Waki, H. et al. (2003) J. Biol. Chem. 278, 40352-40363.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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