Estrogen Receptor alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEstrogen Receptor alpha
Clone[6F11-C3-G6]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2b
Formataffinity purified
Size0.1 mL
Concentration2.85mg/ml
ApplicationsWestern Blot (WB)
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DescriptionEntrez Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
ImmunogenImmunogen: Purified recombinant human Estrogen Receptor alphaMMP-2 protein expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Estrogen Receptor alpha and does not cross-react with related proteins. Sequence Similarities: Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Other Names[Atherosclerosis, susceptibility to, included; DKFZp686N23123; ER Alpha; ER; ER Beta; ER-alpha; ER[a]; ER[b]; Era; ERalpha; Erb; Erb2; ERbeta; ESR; ESR BETA; ESR1; ESR1_HUMAN; ESR2; ESRA; ESRB; Estr; Estra; Estradiol Receptor alpha; Estradiol receptor; Estradiol Receptor beta; ESTRB; Estrogen nuclear receptor alpha; Estrogen receptor 1 (alpha); Estrogen Receptor 1; Estrogen receptor 2 (ER beta); Estrogen Receptor 2; Estrogen receptor 2 ER beta; Estrogen receptor alpha; Estrogen receptor alpha 3*, 4, 5, 6, 7*/822 isoform; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*, 8*/941 isoform; Estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819 2 isoform; Estrogen receptor alpha delta 4 +49 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform; Estrogen receptor alpha delta 4*, 5, 6, 7, 8*/901 isoform; Estrogen receptor alpha E1 E2 1 2; Estrogen receptor alpha E1 N2 E2 1 2; Estrogen receptor; Estrogen receptor beta 4; Estrogen resistance, included; ESTRR; HDL cholesterol, augmented response of, to hormone replacement, included; Myocardial infarction, susceptibility to, included; NR3A1; NR3A2; Nuclear receptor subfamily 3 group A member 1; Nuclear receptor subfamily 3 group A member 2; OTTHUMP00000017718; OTTHUMP00000017719; RNESTROR], [esr1; ER; ESR; Era; ESTRR; NR3A1.]
Gene, Accession #[ESRA;], Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372
Catalog #MBS475265
Price$335
Order / More InfoEstrogen Receptor alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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