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Antigenic Specificity | Human CD52: Low Endotoxin |
Clone | [YTH34.5] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.5 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Cytotoxic Assays (CT), ELISA (EIA), Flow cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistology Paraffin, Immunohistology Resin (RE), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link (Xia et al. 1991). The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kDa, considerably reduced following N-glycanase treatment (Rowan et al. 1998). CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies (Deard |
Immunogen | n/a |
Other Names | [CAMPATH-1 antigen; CAMPATH-1 antigen; CAMPATH-1 antigen; CD52 antigen (CAMPATH-1 antigen); CDW52 antigen (CAMPATH-1 antigen); HEL-S-171mP; cambridge pathology 1 antigen; epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; human epididymis-specific protein 5; CD52 molecule; CDw52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5; He5; CD_antigen: CD52], [CD52; CD52; CDW52; CDW52; HE5; He5] |
Gene, Accession # | [CD52], Gene ID: 1043, NCBI: NP_001794.2, UniProt: P31358 |
Catalog # | MBS215123 |
Price | $750 |
Order / More Info | Human CD52: Low Endotoxin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |