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Antigenic Specificity | Phospho-TNNI3 (Thr142) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-TNNI3 (Thr142) antibody detects endogenous levels of TNNI3 only when phosphorylated at Threonine 142. Description: Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1 (MIM 191042). The others are troponin T (TnT; see MIM 191041) and troponin C (TnC; see MIM 191040).Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.Subunit Structure: Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1.Post-translational Modifications: Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation incre |
Immunogen | Immunogen: A synthesized peptide derived from human TNNI3 around the phosphorylation site of Threonine 142 Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (93%), Dog (100%) |
Other Names | [cardiac muscle; Cardiac troponin I; cardiomyopathy, dilated 2A (autosomal recessive); Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; TNNI3_HUMAN; Troponin I; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; Ttroponin I type 3 (cardiac)] |
Gene, Accession # | [TNNI3], Gene ID: 7137, NCBI: NP_000354.4, UniProt: P19429 |
Catalog # | MBS9600985 |
Price | $240, $280 |
Order / More Info | Phospho-TNNI3 (Thr142) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |