Phospho-TNNI3 (Thr142) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-TNNI3 (Thr142)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phospho-TNNI3 (Thr142) antibody detects endogenous levels of TNNI3 only when phosphorylated at Threonine 142. Description: Troponin I (TnI) is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle; see also TNNI1 (MIM 191042). The others are troponin T (TnT; see MIM 191041) and troponin C (TnC; see MIM 191040).Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.Subunit Structure: Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1.Post-translational Modifications: Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation incre
ImmunogenImmunogen: A synthesized peptide derived from human TNNI3 around the phosphorylation site of Threonine 142 Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (93%), Dog (100%)
Other Names[cardiac muscle; Cardiac troponin I; cardiomyopathy, dilated 2A (autosomal recessive); Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; TNNI3_HUMAN; Troponin I; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; Ttroponin I type 3 (cardiac)]
Gene, Accession #[TNNI3], Gene ID: 7137, NCBI: NP_000354.4, UniProt: P19429
Catalog #MBS9600985
Price$240, $280
Order / More InfoPhospho-TNNI3 (Thr142) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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