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Antigenic Specificity | ALK (Phospho Tyr1507) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ALK (Y1507) Polyclonal Antibody detects endogenous levels of ALK protein only when phosphorylated at Y1507. ALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common |
Immunogen | Immunogen: Synthesized peptide derived from human ALK around the phosphorylation site of Y1507 |
Other Names | [Rabbit ALK (phospho Tyr1507); ALK; ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD antigen CD246] |
Gene, Accession # | [ALK], Gene ID: 238, NCBI: NP_004295.2, UniProt: Q9UM73 |
Catalog # | MBS9705025 |
Price | $130, $220, $325 |
Order / More Info | ALK (Phospho Tyr1507) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |