FoxO3a Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-FoxO3a antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | FoxO3a |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to FoxO3a. The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias (1-3). Within the family, three members (FoxO1, FoxO4, and FoxO3a) have sequence similarity to the nematode orthologue DAF-16, which mediates signaling via a pathway involving IGFR1, PI3K, and Akt (4-6). Active forkhead members act as tumor suppressors by promoting cell cycle arrest and apoptosis. Increased expression of any FoxO member results in the activation of the cell cycle inhibitor p27 Kip1. Forkhead transcription factors also play a part in TGF-beta-mediated upregulation of p21 Cip1, a process negatively regulated through PI3K (7). Increased proliferation results when forkhead transcription |
| Immunogen | Immunogen: A synthetic -peptide of human FoxO3a |
| Other Names | [FOXO3; FoxO3a; FoxO3a; FOXO3; AF6q21; DKFZp781A0677; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; MGC12739; MGC31925], [FOXO3; FOXO3; FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; FKHRL1; FOXO3A] |
| Gene, Accession # | Gene ID: 2309, NCBI: NP_001446.1, UniProt: O43524 |
| Catalog # | MBS125231 |
| Price | $200, $275, $430 |
| Order / More Info | FoxO3a Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Anderson, M.J. et al. (1998) Genomics 47, 187-199. 2. Galili, N. et al. (1993) Nat. Genet. 5, 230-235. 3. Borkhardt, A. et al. (1997) Oncogene 14, 195-202. 4. Nakae, J. et al. (1999) J. Biol. Chem. 274, 15982-15985. 5. Rena, G. et al. (1999) J. Biol. Chem. 274, 17179-17183. 6. Guo, S. et al. (1999) J. Biol. Chem. 274, 17184-17192. 7. Seoane, J. et al. (2004) Cell 117, 211-223. 8. Arden, K.C. (2004) Mol. Cell 14, 416-418. 9. Yang, Y. et al. (2005) EMBO J. 24, 1021-1032. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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