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Antigenic Specificity | Insulin Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Insulin receptor(INSR) detection. Tested with WB in Human, Mouse, Rat. Background: INSR(INSULIN RECEPTOR) is a tetramer of 2 alpha and 2 beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor gene is mapped to 19p13.2. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on bind |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Insulin Receptor (1353-1372aa RSYEEHIPYTHMNGGKKNGR), different from the related rat and mouse sequences by two amino acids. |
Other Names | [Insulin receptor(IR); insulin receptor; CD 220; CD220; CD220 antigen; HHF 5; HHF5; human insulin receptor; INSR; INSR_HUMAN; Insulin receptor subunit beta; IR 1; IR; IR-1; IR1], [INSR; INSR; HHF5; CD220; IR] |
Gene, Accession # | [INSR], Gene ID: 3643, NCBI: P06213.4, UniProt: P06213 |
Catalog # | MBS175106 |
Price | $280 |
Order / More Info | Insulin Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |