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Antigenic Specificity | TRIB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted cross reactivity with mouse samples |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect TRIB1 in human samples. TRIB1 antibody; also called gprotein coupled receptor induced; skip1; gig2; c8fwATP; functions in protein binding; protein kinase inhibitor activity; and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras-driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3; and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1; indicating that the TRIB-MAPKK interacti |
Immunogen | Immunogen: This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1 |
Other Names | [Tribbles homolog 1; TRB-1; G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1; TRIB1], [TRIB1; TRIB1; C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1; TRB-1; GIG-2] |
Gene, Accession # | [TRIB1], Gene ID: 10221, NCBI: NP_001269914.1, UniProt: Q96RU8 |
Catalog # | MBS845530 |
Price | $305 |
Order / More Info | TRIB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |