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Antigenic Specificity | MAPK1 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrate |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 300-350 on human Mitogen-activated protein kinase 1. Conjugation: Unconjugated |
Other Names | [Affinity Purified Mitogen-activated protein kinase 1; ERK; ERK-2; ERT1; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase isoform p42; MAPK 1; Mapk1; MAPK2; Mitogen-activated protein kinase 1; P38; P40; P41; p42-MAPK; P42MAPK; PRKM1; protein kinase, mitogen-activated, 1] |
Gene, Accession # | [MAPK1], Gene ID: 5594, NCBI: NP_002736.3, UniProt: P28482 |
Catalog # | MBS5400489 |
Price | $390 |
Order / More Info | MAPK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |