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Antigenic Specificity | Paxillin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PXN (paxillin) is a 68 kDa scaffold protein that interacts with multiple structural and signaling proteins and regulates cell adhesion, migration, proliferation, and apoptosis. PXN is thought to play an important role in tumor migration, invasion, and metastasis (21045234). PXN has been identified as a direct substrate of protein tyrosine phosphatase receptor-type T (PTPRT), a potent tumor suppressor gene. Increased phospho-PXN at tyrosine residue 88 (Y88) has been found as a common feature of human colon cancers (20133777). |
Immunogen | Immunogen: Recombinant protein of human PXN Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [paxillin isoform 2; Paxillin; paxillin; paxillin] |
Gene, Accession # | [PXN], Gene ID: 5829, NCBI: NP_001074324.1, UniProt: P49023 |
Catalog # | MBS8505377 |
Price | $310 |
Order / More Info | Paxillin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |