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Antigenic Specificity | BIRC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BIRC2 protein. The inhibitor of apoptosis protein (IAP) family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 amino acid BIR (baculovirus inhibitor repeat) domain (1,2). Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression (3-5). In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9 (5,6). In addition, binding of IAP family members to th |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BIRC2. |
Other Names | [BIRC2; API1; HIAP2; Hiap-2; MIHB] |
Gene, Accession # | [BIRC2], Gene ID: 329, NCBI: NP_001157.1, UniProt: Q13490 |
Catalog # | MBS9401258 |
Price | $255 |
Order / More Info | BIRC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |