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Antigenic Specificity | HLA-DOB - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, porcine, rabbit, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against HLA-DOB. It was validated on Western BlotTarget Description: HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HLA-DOB |
Other Names | [HLA class II histocompatibility antigen, DO beta chain; HLA class II histocompatibility antigen, DO beta chain; major histocompatibility complex, class II, DO beta] |
Gene, Accession # | [HLA-DOB], Gene ID: 3112, NCBI: NP_002111, UniProt: Q5QNS2 |
Catalog # | MBS3215313 |
Price | $335 |
Order / More Info | HLA-DOB - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |