Human Low density lipoprotein receptor adapter protein 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Low density lipoprotein receptor adapter protein 1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. |
| Immunogen | Immunogen: Recombinant human Low density lipoprotein receptor adapter protein 1 protein (59-308aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26734 / sc-130692 / sc-292294 |
| Other Names | [Autosomal recessive hypercholesterolemia protein; LDLRAP1; ARH], [LDLRAP1; LDLRAP1; ARH; ARH1; ARH2; FHCB1; FHCB2; ARH] |
| Gene, Accession # | [LDLRAP1], Gene ID: 26119, NCBI: NP_056442.2, UniProt: Q5SW96 |
| Catalog # | MBS1493216 |
| Price | $120, $160 |
| Order / More Info | Human Low density lipoprotein receptor adapter protein 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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