SMAC Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SMAC |
| Clone | [AT19F2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, k |
| Format | Protein A purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SMAC/Diablo is one of the proapoptotic proteins. SMAC promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. In healthy cells, SMAC is a mitochondrial protein, but when cells undergo apoptosis, SMAC is released into the cytosol. SMAC is ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes |
| Immunogen | Immunogen: Recombinant human SMAC/Diablo (56-239aa) purified from E. coli |
| Other Names | [Diablo isoform 1; SMAC3; DIABLO-S; FLJ10537; FLJ25049; Diablo isoform 1; SMAC/Diablo; Diablo isoform 1 0610041G12Rik; DBOH; Diablo homolog; DIABLO S; Diablo homolog (Drosophila); Mitochondrial Smac protein; Diablo homolog mitochondrial; SMAC 3; Smac protein; Direct IAP binding protein with low pI; Second mitochondria derived activator of caspase.], [DIABLO; DIABLO; SMAC; DFNA64; SMAC; Smac] |
| Gene, Accession # | [SMAC], Gene ID: 56616, NCBI: NP_063940, UniProt: Q9NR28 |
| Catalog # | MBS200261 |
| Price | $240, $315 |
| Order / More Info | SMAC Antibody from MYBIOSOURCE INC. |
| Product Specific References | McNeish. I.A., et al. (2003) Exp Cell Res 286 (2): 186-198; Yu. J., et al. (2007) Oncogene 26 (29): 4189-4198 ; Vucic. D., et al. (2002) J Biol Chem 277 (14): 12275-12279 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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