GPS2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGPS2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein. GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
ImmunogenImmunogen: Synthesized peptide derived from the N-terminal region of human GPS2 at AA rangle: 30-110
Other Names[Rabbit GPS2; GPS2; G protein pathway suppressor 2; GPS-2]
Gene, Accession #[GPS2], Gene ID: 2874, NCBI: NP_004480.1, UniProt: Q13227
Catalog #MBS9705268
Price$130, $220, $325
Order / More InfoGPS2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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