FE65 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | FE65 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | mouse. predicted to work with: human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Amyloid beta A4 precursor protein-binding family B member 1(APBB1) detection. Tested with WB in Human;Mouse. Background: APBB1 is also known as RIR or FE65. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It |
| Immunogen | Immunogen: E Coli-derived human FE65 recombinant protein (Position: Q295-A613). Human FE65 shares 95%and 96% amino acid (aa) sequence identity with mouse and rat FE65, respectively. |
| Other Names | [Amyloid beta A4 precursor protein-binding family B member 1; Adaptor protein FE65a2; Amyloid beta (A4) precursor protein binding family B member 1; Amyloid Beta A4 Precursor Protein Binding Family B; Amyloid beta A4 precursor protein binding family B member 1; Amyloid beta A4 precursor protein-binding family B member 1; Amyloid beta precursor protein binding family B member 1; APBB 1; APBB1; APBB1_HUMAN; FE 65; Fe65 protein; Protein Fe65; RIR; stat like protein; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)], [APBB1; APBB1; RIR; FE65; MGC:9072; FE65; RIR] |
| Gene, Accession # | [FE65], Gene ID: 322, NCBI: NP_001155.1, UniProt: O00213 |
| Catalog # | MBS178400 |
| Price | $280 |
| Order / More Info | FE65 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chen GB, et al. Association of amyloid precursor protein-binding protein, family B, member 1 with nicotine dependence in African and European American smokers. Hum Genet, 2008 Nov. 2. Cheung HN, et al. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J, 2014 Jan. 3. Ward MW, et al. The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics. J Neurochem, 2010 Apr. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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