Edit |   |
---|---|
Antigenic Specificity | RNF19A - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.Target Description: RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING finger |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A |
Other Names | [E3 ubiquitin-protein ligase RNF19A; E3 ubiquitin-protein ligase RNF19A; E3 ubiquitin-protein ligase RNF19A; ring finger protein 19A, RBR E3 ubiquitin protein ligase; Double ring-finger protein; Dorfin; RING finger protein 19A; p38] |
Gene, Accession # | [RNF19A], Gene ID: 25897, NCBI: NP_056250, UniProt: Q9NV58 |
Catalog # | MBS3206758 |
Price | $365 |
Order / More Info | RNF19A - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |