BACE1B (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBACE1B (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionThis BACE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human BACE1B. Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, betwe
Immunogenn/a
Other Names[Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; BACE; KIAA1149]
Gene, Accession #[BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817
Catalog #MBS9217128
Price$165, $370
Order / More InfoBACE1B (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesChristensen, M.A., et al., Mol. Cell. Biol. 24 (2):865-874 (2004). Lichtenthaler, S.F., et al., J. Biol. Chem. 278 (49):48713-48719 (2003). Hussain, I., et al., J. Biol. Chem. 278 (38):36264-36268 (2003). Basi, G., et al., J. Biol. Chem. 278 (34):31512-31520 (2003). Clarimon, J., et al., J. Neurol. 250 (8):956-961 (2003).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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