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Antigenic Specificity | c-Myc |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Myc proto-oncogene protein(MYC) detection. Tested with WB in Human, Mouse, Rat. Background: C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol(2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human c-Myc (421-439aa RKRREQLKHKLEQLRNSCA), different from the related mouse and rat sequences by one amino acid. |
Other Names | [Myc proto-oncogene protein; v-myc myelocytomatosis viral oncogene homolog(avian); AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; c Myc Epitope Tag; c Myc Tag; Class E basic helix-loop-helix protein 39; MRTL; Myc; Myc Epitope Tag; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; MYC_HUMAN; Myc2; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; OTTHUMP00000158589; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog(avian)], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: P01106.1, UniProt: P01106 |
Catalog # | MBS175271 |
Price | $280 |
Order / More Info | c-Myc Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |