c-Myc Antibody from MYBIOSOURCE INC.

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Antigenic Specificityc-Myc
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Myc proto-oncogene protein(MYC) detection. Tested with WB in Human, Mouse, Rat. Background: C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol(2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human c-Myc (421-439aa RKRREQLKHKLEQLRNSCA), different from the related mouse and rat sequences by one amino acid.
Other Names[Myc proto-oncogene protein; v-myc myelocytomatosis viral oncogene homolog(avian); AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; c Myc Epitope Tag; c Myc Tag; Class E basic helix-loop-helix protein 39; MRTL; Myc; Myc Epitope Tag; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; MYC_HUMAN; Myc2; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; OTTHUMP00000158589; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog(avian)], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]
Gene, Accession #[MYC], Gene ID: 4609, NCBI: P01106.1, UniProt: P01106
Catalog #MBS175271
Price$280
Order / More Infoc-Myc Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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