Edit |   |
---|---|
Antigenic Specificity | Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) |
Clone | [KRT15/2554] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Frozen & Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. |
Immunogen | Immunogen: Recombinant full-length human KRT15 protein Positive Control: HeLa or A431 Cells. Skin or Colon. |
Other Names | [CK15; Cytokeratin 15; K1CO; Ka15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; KRT15; KRTB; KRTL15; Type I cytoskeletal 15; Type I keratin Ka15] |
Gene, Accession # | [KRT15], Gene ID: 3866, NCBI: NP_002266.2, UniProt: P19012 |
Catalog # | MBS4380610 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yu-Hong Shen, et al. Asian Pac J Cancer Prev, 17 (9), 4217-4222. |