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Antigenic Specificity | LNPEP (N-Term), 23-52 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LNPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human LNPEP. This gene encodes a zinc-dependent aminopeptidase thatcleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin,dynorphin A and other peptide hormones. The protein can be secretedin maternal serum, reside in intracellular vesicles with theinsulin-responsive glucose transporter GLUT4, or form a type IIintegral membrane glycoprotein. The protein catalyzes the finalstep in the conversion of angiotensinogen to angiotensin IV (AT4)and is also a receptor for AT4. Alternative splicing results inmultiple transcript variants encoding different isoforms |
Immunogen | n/a |
Other Names | [Leucyl-cystinyl aminopeptidase; Cystinyl aminopeptidase; Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Oxytocinase; OTase; Placental leucine aminopeptidase; P-LAP; Leucyl-cystinyl aminopeptidase; pregnancy serum form; LNPEP; OTASE] |
Gene, Accession # | [LNPEP], Gene ID: 4012, NCBI: NP_005566.2, UniProt: Q9UIQ6 |
Catalog # | MBS9209248 |
Price | $165, $370 |
Order / More Info | LNPEP (N-Term), 23-52 Antibody from MYBIOSOURCE INC. |
Product Specific References | Georgiadou, D., et al. J. Immunol. 185(3):1584-1592(2010) Williams, P.J., et al. Placenta 31(5):448-455(2010) Landau, R., et al. Neuro Endocrinol. Lett. 31(1):63-66(2010) Johnson, M.P., et al. Hum. Genet. 126(5):655-666(2009) Saveanu, L., et al. Science 325(5937):213-217(2009) |