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Antigenic Specificity | FEN1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against FEN1. It was validated on Western BlotTarget Description: FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap th |
Immunogen | n/a |
Other Names | [flap endonuclease 1; Flap endonuclease 1; flap endonuclease 1; flap structure-specific endonuclease 1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1] |
Gene, Accession # | [FEN1], Gene ID: 2237, NCBI: NP_004102, UniProt: P39748 |
Catalog # | MBS3208050 |
Price | $335 |
Order / More Info | FEN1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |