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Antigenic Specificity | ENO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Enolase is an important glycolytic enzyme involved in the interconversion of 2-phosphoglycerate to phosphoenolpyruvate. Mammalian enolase exists as three subunits: enolase-1 (alpha-enolase), enolase-2 (gamma-enolase) and enolase-3 (beta-enolase) that can form both homo- and heterodimers. Expression of the enolase isoforms differs in a tissue specific manner (1). Enolase-1 plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion (2,3). Abnormal expression of enolase-1 is associated with tumor progression in some cases of breast and lung cancer (4-7). Alternatively, an enolase-1 splice variant (MBP-1) binds the c-myc promoter p2 and may function as a tumor supp |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [ENO1; ENO1L1; MBP-1; MPB1; NNE; PPH], [ENO1; ENO1; NNE; PPH; MPB1; ENO1L1; ENO1L1; MBPB1; MPB1; NNE] |
Gene, Accession # | [ENO1], Gene ID: 2023, NCBI: P06733.2, UniProt: P06733 |
Catalog # | MBS127077 |
Price | $200, $275, $430 |
Order / More Info | ENO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |