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Antigenic Specificity | Nibrin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Nibrin Polyclonal Antibody detects endogenous levels of Nibrin protein. Mutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Nibrin at AA range: 400-480 |
Other Names | [Rabbit Nibrin; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1] |
Gene, Accession # | [NBN], Gene ID: 4683, NCBI: NP_002476.2, UniProt: O60934 |
Catalog # | MBS9702651 |
Price | $130, $220, $325 |
Order / More Info | Nibrin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |