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Antigenic Specificity | TRAF4 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions. |
Immunogen | Immunogen: A synthesized peptide derived from human TRAF4. Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Tissue Specificity: Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus. |
Other Names | [TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83; TRAF4; CART1; MLN62; RNF83], [TRAF4; TRAF4; CART1; MLN62; RNF83; CART1; MLN62; RNF83; MLN 62] |
Gene, Accession # | [TRAF4], Gene ID: 9618, NCBI: NP_004286.2, UniProt: Q9BUZ4 |
Catalog # | MBS179933 |
Price | $160, $340, $340 |
Order / More Info | TRAF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |