CREB3L2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CREB3L2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CREB3L2 antibody detects endogenous levels of total CREB3L2. Function: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cart |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Endoplasmic Reticulum Membrane and Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. Tissue Specificity: Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabb |
| Other Names | [B ZIB transcription factor; Basic transcription factor 2; BBF2 human homolog on chromosome 7; BBF2H7; BZIB transcription factor; cAMP responsive element binding protein 3 like 2; cAMP-responsive element-binding protein 3-like protein 2; CR3L2_HUMAN; Creb3l2; Cyclic AMP-responsive element-binding protein 3-like protein 2; FUS/BBF2H7 protein; MGC131709; MGC71006; Processed cyclic AMP-responsive element-binding protein 3-like protein 2; TCAG_1951439] |
| Gene, Accession # | [CREB3L2], Gene ID: 64764, NCBI: NP_001240704.1, UniProt: Q70SY1 |
| Catalog # | MBS9606116 |
| Price | $240, $280 |
| Order / More Info | CREB3L2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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