ADRB2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ADRB2 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | rat. predicted to work with: human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Beta-2 adrenergic receptor(ADRB2) detection. Tested with WB in Human;Rat. Background: ADRB2, also known as beta-2 adrenergic receptor, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It is mapped to 5q32. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. The genetic variation in the ADRB2 gene may be of major importance for obesity, energy expenditure, and lipolytic ADRB2 function in adipose tissue, at least in women. What's more, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activi |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ADRB2(221-256aa RVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH), different from the related mouse and rat sequences by three amino acids. Ig Type: Rabbit IgG |
| Other Names | [Beta-2 adrenergic receptor; ADRB2; Alpha PAK; Alpha-PAK; MGC130000; MGC130001; p21 activated kinase 1; p21 protein (Cdc42/Rac) activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p65 PAK; p65-PAK; P68-PAK; PAK alpha; PAK-1; Pak1; PAK1_HUMAN; Paka; PAKalpha; Protein kinase MUK2; Rac/p21-activated kinase; Serine/threonine-protein kinase PAK 1; STE20 homolog yeast; adrenoceptor beta 2, surface], [ADRB2; ADRB2; BAR; B2AR; ADRBR; ADRB2R; BETA2AR; ADRB2R; B2AR; Beta-2 adrenoceptor] |
| Gene, Accession # | [ADRB2], Gene ID: 154, NCBI: NP_000015.1, UniProt: P07550 |
| Catalog # | MBS177932 |
| Price | $280 |
| Order / More Info | ADRB2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: ADRB2 adrenergic, beta-2-, receptor, surface 2. Large, V., Hellstrom, L., Reynisdottir, S., Lonnqvist, F., Eriksson, P., Lannfelt, L., Arner, P.Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function. J. Clin. Invest. 100: 3005-3013, 1997. 3. Ni, Y., Zhao, X., Bao, G., Zou, L., Teng, L., Wang, Z., Song, M., Xiong, J., Bai, Y., Pai, G.Activation of beta-2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation. Nature Med. 12: 1390-1396, 2006. |
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MYBIOSOURCE INC.
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