Paxillin (Ser-178), phospho-specific Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Paxillin (Ser-178), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects a 68kDa* protein corresponding to the molecular mass of phosphorylated paxillin on SDS-PAGE immunoblots of EGF treated A431 cells, but not in A431 control cells. Similar results were seen in calyculin A treated human A431 and aortic endothelial cells. Paxillin, a focal adhesion protein, is involved in focal adhesion formation during cell adhesion and migration. Paxillin contains LD motifs, LIM domains, and SH3-/SH2-binding domains that participate in a variety of protein-protein interactions with kinases, GTPase-activating proteins, and cytoskeletal proteins. Phosphorylation of paxillin occurs at both tyrosine and serine sites. Serine phosphorylation of paxillin occurs in response to growth-factor activation and fibron |
| Immunogen | Immunogen: Phospho-Paxillin (Ser-178) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 178 of human paxillin. This human sequence is highly conserved in rat and mouse paxillin. |
| Other Names | [Paxillin (Ser-178); phospho-specific; Paxillin], [Pxn; Pxn; Pxn] |
| Gene, Accession # | Gene ID: 360820, NCBI: NP_001012147.1, UniProt: Q66H76 |
| Catalog # | MBS472047 |
| Price | $385 |
| Order / More Info | Paxillin (Ser-178), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Huang, C. et al. (2003) Nature 424:219-223.• Huang, C. et al. (2004) Cell Cycle 3(1):4-6.• Woodrow, M.A. (2003) Exp. Cell. Res. 287(2):325-338. |
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MYBIOSOURCE INC.
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