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Antigenic Specificity | ATG4D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human; predicted reactivity: mouse, porcine |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326~356 amino acids surrounding S341 of human APG4D. Description: APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation |
Immunogen | n/a |
Other Names | [Cysteine protease ATG4D; 3422-; AUT-like 4 cysteine endopeptidase; Autophagin-4; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; mitochondrial; ATG4D; APG4D; AUTL4] |
Gene, Accession # | [ATG4D], Gene ID: 84971, NCBI: NP_001268433.1, UniProt: Q86TL0 |
Catalog # | MBS9217095 |
Price | $165, $370 |
Order / More Info | ATG4D Antibody from MYBIOSOURCE INC. |
Product Specific References | Baehrecke EH. Nat Rev Mol Cell Biol. 6 (6):505-10. (2005). Lum JJ, et al. Nat Rev Mol Cell Biol. 6 (6):439-48. (2005). Greenberg JT. Dev Cell. 8 (6):799-801. (2005). Levine B. Cell. 120 (2):159-62. (2005). Shintani T and Klionsky DJ. Science. 306 (5698):990-5. (2004). |