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Antigenic Specificity | ASH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Chromatin Immunoprecipitation (ChIP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect Ash2 in mouse samples. Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against mouse Ash2 (absent, small, or homeotic 2), using 3 different KLH-conjugated synthetic peptides, 2 containing an amino acid sequence from the central and 1 containing an amino acid sequence from the C-terminal part of the protein. Positive Control: Western blot: mouse fibroblasts and neural stem cells, ELISA: Peptides, IF: NIH3T3 cells. |
Other Names | [ASH2L; ASH2L1; ASH2L2; Bre2], [ASH2L; ASH2L; ASH2; Bre2; ASH2L1; ASH2L2; ASH2L1] |
Gene, Accession # | [ASH2], Gene ID: 9070, NCBI: NP_001098684.1, UniProt: Q9UBL3 |
Catalog # | MBS841240 |
Price | $290 |
Order / More Info | ASH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |