Edit |   |
---|---|
Antigenic Specificity | ITGB4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6: ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed: 20682778). ITGA6: ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed: 22351760). |
Immunogen | Immunogen: Recombinant Human Integrin beta-4 protein (1401-1533AA) |
Other Names | [Integrin beta-4; GP150; CD104; ITGB4] |
Gene, Accession # | [ITGB4], Gene ID: 3691, NCBI: NP_000204.3, UniProt: P16144 |
Catalog # | MBS7048493 |
Price | $160, $235 |
Order / More Info | ITGB4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |