Human Lipopolysaccharide-induced TNF factor Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Lipopolysaccharide-induced TNF factor |
| Clone | [PAT1F9AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. LITAF is a lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of the LITAF gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in the LITAF gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget''s disease (EMPD). |
| Immunogen | Immunogen: Anti-human LITAF mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LITAF amino acids 1-161 purified from E Coli. |
| Other Names | [LITAF; Lipopolysaccharide-induced TNF factor, Mouse Human; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; LPS-induced TNF-alpha factor; p53-induced gene 7 protein; Small integral membrane protein of lysosome/late endosome; LITAF; PIG7; SIMPLE; TP53I7; FLJ38636; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276], [LITAF; LITAF; PIG7; SIMPLE; TP53I7; PIG7; SIMPLE; LPS-induced TNF-alpha factor] |
| Gene, Accession # | [LITAF], Gene ID: 9516, NCBI: NP_001129944.1 |
| Catalog # | MBS140281 |
| Price | $140, $205, $505 |
| Order / More Info | Human Lipopolysaccharide-induced TNF factor Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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