Edit |   |
---|---|
Antigenic Specificity | SSRP1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SSRP1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. It also functions as a co-activator of the transcriptional activator p63.The protein encoded by this gene is a subunit of a heterodimer that, a |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSRP1 |
Other Names | [FACT complex subunit SSRP1; FACT complex subunit SSRP1; FACT complex subunit SSRP1; structure specific recognition protein 1; Chromatin-specific transcription elongation factor 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; FACT 80 kDa subunit; FACTp80; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognition protein 1; Structure-specific recognition protein 1; hSSRP1; T160] |
Gene, Accession # | [SSRP1], Gene ID: 6749, NCBI: NP_003137, UniProt: Q08945 |
Catalog # | MBS3203981 |
Price | $335 |
Order / More Info | SSRP1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |