Cyclin E1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCyclin E1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, bovine, dog, porcine
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
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DescriptionPolyclonal Antibody to detect Cyclin E1 in human, mouse, rat, bovine, dog and pig samples. Background: Cyclin E1 is a regulatory subunit of the CDK2 kinase. It is central for the regulation of the G1/S transition and its abundance is tightly regulated throughout the cell cycle via ubiquitination. Cyclin E has been the subject of intense study in relation to tumorigenesis and cancer management and prognosis. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse
ImmunogenImmunogen: This Cyclin E1 antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin E1. The exact sequence is proprietary. Positive Control: WB: HEK293T, mouse brain, PC12, SW626, HeLa, K562, whole cell lysates, IHC: human lung cancer, IC/IF: PC12 cells
Other Names[CCNE1; Cyclin Es; Cyclin Et; G1/S-specific cyclin-E1], [CCNE1; CCNE1; CCNE; pCCNE1; CCNE]
Gene, Accession #Gene ID: 898, NCBI: NP_001229.1, UniProt: P24864
Catalog #MBS840321
Price$240
Order / More InfoCyclin E1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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