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Antigenic Specificity | MCL1 (Center), 217-245 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.49 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the Central region of human MCL1. This gene encodes an anti-apoptotic protein, which is amember of the Bcl-2 family. Alternative splicing results inmultiple transcript variants. The longest gene product (isoform 1)enhances cell survival by inhibiting apoptosis while thealternatively spliced shorter gene products (isoform 2 and isoform3) promote apoptosis and are death-inducing. |
Immunogen | n/a |
Other Names | [Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EAT; MCL1; BCL2L3] |
Gene, Accession # | [MCL1], Gene ID: 4170, NCBI: NP_001184249.1, UniProt: Q07820 |
Catalog # | MBS9212922 |
Price | $165, $370 |
Order / More Info | MCL1 (Center), 217-245 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kim, J.H., et al. FEBS Lett. 583(17):2758-2764(2009) Maurer, U., et al. Mol. Cell 21(6):749-760(2006) Domina, A.M., et al. Oncogene 23(31):5301-5315(2004) |