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Antigenic Specificity | ANXA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ANXA1 antibody detects endogenous levels of total ANXA1. Description: The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology (1). Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis (2-4). Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity (5, 6). Annexin A1 can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation (7). Phosphorylation by PKC, EGFR, and Chak1 results in inhibition of annexin A1 f |
Immunogen | Immunogen: A synthesized peptide derived from human ANXA1 Subcellular Location: Nucleus. Cytoplasm. Cell Projection > Cilium. Basolateral Cell Membrane. Found in the cilium, nucleus and basolateral Cell Membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages. Tissue Specificity: Detected in resting neutrophils (PubMed:10772777). Detected in peripheral blood T-cells (PubMed:17008549). Detected in extracellular |
Other Names | [Annexin 1; Annexin A1; Annexin I (lipocortin I); Annexin I; Annexin-1; AnnexinA1; AnnexinI; ANX 1; ANX A1; ANX1; ANXA 1; ANXA1; ANXA1 protein; ANXA1_HUMAN; Calpactin 2; Calpactin II; Calpactin-2; CalpactinII; Chromobindin 9; Chromobindin-9; Chromobindin9; HGNC:533; Lipocortin 1; Lipocortin I; Lipocortin1; LipocortinI; LPC 1; LPC1; p35; Phospholipase A2 inhibitory protein] |
Gene, Accession # | [ANXA1], Gene ID: 301, NCBI: NP_000691.1, UniProt: P04083 |
Catalog # | MBS9606913 |
Price | $240, $280 |
Order / More Info | ANXA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |